![]() ![]() Unexplained lymphadenopathy: evaluation and differential diagnosis. Unintentional weight loss in older adults. Selective serotonin reuptake inhibitors and night sweats in a primary care population. Grigoropoulos NF, Petter R, Van 't Veer MB, et al. Fruit, Mediterranean-style, and high-fat and -sugar diets are associated with the risk of night sweats and hot flushes in midlife: results from a prospective cohort study. ![]() Nocturnal sweating-a common symptom of obstructive sleep apnoea: the Icelandic sleep apnoea cohort. ![]() Associations between subjective night sweats and sleep study findings. Associations between night sweats and other sleep disturbances: an OKPRN study. Are night sweats a sign of esophageal reflux?. Prevalence and predictors of night sweats, day sweats, and hot flashes in older primary care patients: an OKPRN study. Risk factors for night sweats and hot flushes in midlife: results from a prospective cohort study. Herber-Gast GM, Mishra GD, van der Schouw YT, et al. Clinical aspects of uncomplicated and severe malaria. HACEK infective endocarditis: characteristics and outcomes from a large, multinational cohort. International Collaboration on Endocarditis Prospective Cohort Study Investigators. A practical guide to male hypogonadism in the primary care setting. Night sweats in children: prevalence and associated factors. The prognostic implications of night sweats in two cohorts of older patients. Night sweats: a systematic review of the literature. Prevalence of night sweats in primary care patients: an OKPRN and TAFP-Net collaborative study. Women age 30s to 60s, menstrual changes, vasomotor symptomsįollicle-stimulating hormone (may be normal at early stage), treatment of vasomotor symptoms Trial of proton pump inhibitor or histamine H 2 blockerĬomplete blood count, heterophile antibodies (consider antiviral capsid antigen immune globulin M) Generalized sweating, headache, labile hypertension, paroxysms of palpitationsĢ4-hour urine catecholamines or metanephrines, plasma if elevated, the tumor must be localized using radiologic imaging Test blood glucose during typical episodeĮxcessive daytime sleepiness, Mallampati III or IV oropharynx, observed snoring or gasping during sleep, overweightįirm lymphadenopathy without recent infection The presence of night sweats alone does not indicate an increased risk of death.Ībdominal cramping, attacks of cyanotic flushing, edema, hypotension, watery diarrhea, wheezingĢ4-hour urine 5-hydroxyindoleacetic acid certain foods may cause false-positive results if elevated, the tumor must be localized using radiologic imagingĪnxiety, diarrhea, exophthalmos, heat intolerance, tachycardia, tremorĬough, fever, high-risk sexual activity, history of exposure to tuberculosis, immunocompromise, intravenous drug use, Janeway lesions, new heart murmur, Osler nodes, splinter hemorrhages, travel, weight lossĬomplete blood count, purified protein derivative or interferon-gamma release assay, chest radiography, HIV test (CD4+ count if known to be HIV-positive), blood cultures to include HACEK organisms, echocardiography If these results are normal, and no additional disorders are suspected, reassurance and continued monitoring are recommended. Additional tests that could be considered selectively include computed tomography of the chest and/or abdomen, bone marrow biopsy, polysomnography, and/or additional laboratory studies if indicated. When the history and physical examination do not reveal a specific cause, physicians should proceed with a systematic and cost-conscious strategy that uses readily available laboratory and imaging studies, such as a complete blood count, tuberculosis testing, thyroid-stimulating hormone levels, HIV testing, C-reactive protein level, and chest radiography. If a clinical diagnosis is apparent based on the initial history and physical examination, specific treatment for four to eight weeks may be offered. Conditions commonly associated with night sweats include menopause, mood disorders, gastroesophageal reflux disease, hyperthyroidism, and obesity. Although many life-threatening causes such as malignancies or infections have been described, most patients who report persistent night sweats in the primary care setting do not have a serious underlying disorder. Night sweats are a nonspecific symptom that patients commonly experience but rarely discuss with their physicians without prompting.
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